Expression of TRAF2 and its relationship with apoptosis in thyroid carcinoma
- VernacularTitle:肿瘤坏死因子受体相关因子2在甲状腺癌中的表达
- Author:
Yaqing MA
;
Xiaoming LI
;
Xiuying LU
;
Jing MA
- Publication Type:Journal Article
- Keywords:
Receptors,Tumor Necrosis Factor,Type Ⅱ;
Thyroid Neoplasms;
Apoptosis
- From:
Chinese Archives of Otolaryngology-Head and Neck Surgery
2006;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE To investigate the expression of tumor necrosis factor receptor associated factor2(TRAF2) and its relationships with apoptosis in thyroid carcinoma.METHODS SP immunohistochemical staining was used to determine the expression of TRAF2 in 41 specimens of thyroid carcinoma tissue(8 follicular carcinoma and 33 papillary carcinoma) and 9 thyroid adenomas tissues.Simultaneously 7 normal thyroid tissue specimens adjacent to the adenomas were taken as the normal control.RESULTS 1.TRAF2 was found in most thyroid tissue specimens,its positive rates(gray value) in normal tissues,adenomas and carcinomas were 47.15 %(125.03?14.91),66.67 %(116.11?12.67) and 80.49 %(105.11?10.9) respectively.Statistic analysis showed TRAF2 expression in thyroid carcinoma tissues was higher compared to that in adenoma and normal tissues(P
