Effect of somatostatin combined with compound salvia miltiorrhiza injection(复方丹参注射液) on patients with acute pancreatitis
- VernacularTitle:生长抑素联合复方丹参注射液治疗急性胰腺炎临床研究
- Author:
Longyuan JIANG
;
Lili ZHOU
;
Manhui WU
;
Zhengfei YANG
;
Tao YU
;
Zitong HUANG
- Publication Type:Journal Article
- Keywords:
acute pancreatitis;
somatostatin;
compound salvia miltiorrhiza injection
- From:
Chinese Journal of Integrated Traditional and Western Medicine in Intensive and Critical Care
2006;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To observe the therapeutic efficacy of somatostatin combined with compound salvia miltiorrhiza injection(复方丹参注射液)on patients with acute pancreatitis(AP).Methods:By using randomized controlled trail,62 patients with AP were divided into control group(31 cases) and observation group(31 cases) in a period from June,2002 to December,2006.In the control group,routine measures,such as forbidding food,decompressing stomach and intestines,were taken,and in addition,intravenous injection of somatostatin 250 ?g with subsequent intravenous drip 3 000 ?g in normal saline 500 ml at a rate of 250 ?g/h once everyday was used for 7-14 days.On the above treatment of the control group,compound salvia miltiorrhiza injection 20 ml in normal saline 250 ml,intravenous drip every day for 7-14 days,was added in the observation group.The disappearance of symptoms and abdominal signs,amylase of urine and blood,the time of recovery of hepatic function,change of calcium concentration,incidences of multiple organ dysfunction syndrome(MODS) and case fatality were observed and compared.Results:Amylase of blood after treatment in observation group was lower than that in the control group,while serum calcium concentration was higher,especially on 3 and 5 days after treatment(all P
