Dynamic changes of neurokinin A and calcitonin gene-related peptide levels in gastric mucosal and plasma in rats with celiac seawater-immersing trauma
- VernacularTitle:海水浸泡伤大鼠胃黏膜和血浆中神经激肽A和降钙素基因相关肽的动态变化
- Author:
Xiongwei ZHU
;
Weixiong SHI
;
Zhaoshen LI
;
Zhiren FU
;
Guoshan DING
- Publication Type:Journal Article
- Keywords:
Seawater immersion;
Abdominal injuries;
Neurokinin A;
Calcitonin gene-related peptide;
Gastric mucosa
- From:
Chinese Journal of Pathophysiology
2000;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM:To observe the dynamic changes of neurokinin A(NKA) and calcitonin gene-related peptide(CGRP) levels in gastric mucosal and plasma in rats after abdominal seawater-immersing trauma,and to investigate the influence of these two sensory neuropeptides on acute gastric mucosal lesion.METHODS:Thirty-two SD rats were randomly divided into four groups(normal group,celiac seawater-immersing trauma 1,2 and 3 h groups).With emzyoimmunoassay and radioimmunoassay respectively,gastric mucosal and plasma NKA and CGRP levels in rats were measured.RESULTS:Compared with normal rats,with the seawater-immersing time prolonged,gastric mucosal NKA and CGRP levels in rats were progressively decreased(P
