Simultaneous Spectrophotometric Determination of Three Components in Satongfeng Injection by Flexible Tolerance Simplex Method
- VernacularTitle:可变误差多面体分光光度法同时测定撒痛风注射液中3组分的含量
- Author:
Deliang WEI
;
Wanbei GUO
;
Zhihong HUANG
- Publication Type:Journal Article
- Keywords:
Flexible tolerance simplex method;
UV spectrophotometry;
Satongfeng injection;
Sodium salicylate;
Phenazone;
Caffeine;
Content determination
- From:
China Pharmacy
2005;0(16):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To establish a method for simultaneous determination of the contents of three components in synthesis and actual satongfeng injection.METHODS:A flexible tolerance simplex method was used for multi-wavelength spectrophotometry with interval of 1nm in 258～290nm wavelenth,33 wavelenths were selected.RESULTS:The linear range and average recoveries rate of sodium salicylate,phenazone and caffeine were 0～42,0～12,0～6?g?mL-1 and(99.93?0.22)%,(99.85?0.24)% and(100.19?0.40)% respectively.All were agreed with those by standard method.CONCLUSIONS:This method is easy in operation,fast and reproducible,applicable to automatic analysis,and therefore can be used for the quality control of the preparation.
