Preparation and Quality Control of Breviscapine Orally Disintegrating Tablet
- VernacularTitle:灯盏花素口腔崩解片的制备及质量控制
- Author:
Li ZHANG
;
Yanli YU
;
Xiaoming LI
- Publication Type:Journal Article
- Keywords:
Breviscapine orally disintegrating tablet;
Orthogonal experiment;
Quality control
- From:
China Pharmacy
2005;0(15):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJICTIVE: To prepare Breviscapine orally disintegrating tablet and to establish its quality control method. METHODS: The formula of the core of the tablet was optimized with disintegration time as a parameter by an orthogonal design, and the content and the related substances of Breviscapine orally disintegrating tablet were determined by HPLC. RESULTS: The prepared Breviscapine orally disintegrating tablet showed a good stability, and its characters, dissolution, content and the related substances were all in conformity with the related specifications stated in Chinese Pharmacopoeia (2005 edition). CONCLUSION: The methods of preparation and Quality control are simple and feasible.
