Effects of Compound Rhizoma Coptidis Capsules on Hemorheology and Blood Lipid in Rats with Diabetes Mellitus
- VernacularTitle:复方黄连胶囊对糖尿病大鼠血脂及血液流变学的影响
- Author:
Liqin TANG
;
Sheng LIU
;
Liming CHEN
;
Yu WEI
- Publication Type:Journal Article
- Keywords:
Diabetes mellitus;
Compound Rhizoma Coptidis capsules (CRCC);
Lipid metabolism;
Hemorheology
- From:
China Pharmacy
2005;0(15):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE: To study the effects of Compound Rhizoma Coptidis capsule (CRCC) on hemorheology and blood lipid in rats with diabetes mellitus(DM). METHODS: DM model was induced by alloxan. The effects of CRCC on hemorheology and blood lipid in DM rats were observed. RESULTS: The levels of total cholesterol (TC), triglyceride (TG), low density lipoprotein (LDL), very low density lipoprotein (VLDL), lipoprotein, the whole blood viscosity, the whole blood reductive viscosity, aggregation index (AI), rigidity index (IR), distortion deformation transformation index (TK) and fibrinogen (Fib) were all increased by CRCC, while the level of high density lipoprotein (HDL) was increased. CONCLUSION: CRCC can significantly improve the abnormalities in hemorheology and lipid metabolism in DM rats.
