Extraction of 5 Volatile Oils from Rutongxiaojie Granule and Preparation of ?-cyclodextrin Inclusion Compound
- VernacularTitle:乳痛消结颗粒中5种挥发油的提取及?-环糊精包合物的制备
- Author:
Juan HOU
;
Liying DU
;
Junxia MA
- Publication Type:Journal Article
- Keywords:
Rutongxiaojie granules;
Volatile oil;
Extraction;
Inclusion
- From:
China Pharmacy
2005;0(15):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE: To optimize the extraction condition of volatile oil from five medicinal materials in Rutongxiaojie granules and to optimize the inclusion process of the extracted volatile oil. METHODS: The extraction condition was evaluated by orthogonal test with the recovery of volatile oil as indicator; and the inclusion condition was evaluated with the comprehensive scores of recovery ratio of inclusion compound, the content of volatile oil in inclusion compound and the utilization ratio of the volatile oil as criteria. RESULTS: The optimum extraction condition was established as follows: the medicinal materials were soaked in 10 times volume of water for 1hour and distilled for 9h by steam distillation. The optimum inclusion condition was as follows: the proportion of volatile oil to ?-CD was 1∶8; the inclusion temperature was 30℃ and including time was 20min. CONCLUSION: Both the extraction condition and the inclusion condition were reasonable and feasible.
