Study on Preparation and Quality Standard of Jiekang Lotion
- VernacularTitle:洁康洗剂的制备及质量标准研究
- Author:
Ying JI
;
Shailong NIU
;
Zhilin WU
;
Feng SHI
;
Xin LIU
;
Yilei GUO
- Publication Type:Journal Article
- Keywords:
Jiekang lotion;
Preparation;
Quality Standard;
TLC;
HPLC;
Osthde
- From:
China Pharmacy
2005;0(15):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE: To prepare gynecological Jiekang lotion and to establish its quality standard. METHODS: The Caffeotannic acid in Flos Lonicerae, the Berberine in Cortex Phellodendri and the Ammothamnine in Radix Sophorae Flavescentis were identified by TLC; HPLC was adopted to determine the content of Osthole with Hypersil DOS C18 as chromatograpic column. The mobile phase consisted of acetonitrile-water (54∶46) with a flow rate of 1.1mL? min-1. The detection wavelength was set at 321nm. RESULTS: Both the chief components in Jiekang lotion and the corresponding reference substances showed the identical discrimination reactions. The linear range of Osthole was 13～130?g?mL-1. CONCLUSION: The method is sensitive in qualitative reaction, specific in TLC identification, accurate in HPLC quantitation and recurrent. The established standard is applicable for the quality control of Jeikang lotion.
