Determination of Ephedrine Hydrochloride in Antiviral Oral Liquid by HPLC
- VernacularTitle:HPLC法测定抗病毒口服液中盐酸麻黄碱的含量
- Author:
Linli WANG
;
Liang CHEN
;
Ruoqiu FU
;
Zhiyong SONG
- Publication Type:Journal Article
- Keywords:
HPLC;
Antiviral oral liquid;
Ephedrine hydrochloride;
Content determination
- From:
China Pharmacy
2005;0(15):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE: To establish a HPLC method for the determination of the content of Ephedrine hydrochloride in Antiviral oral liquid. METHODS: The determination was performed on Diamonsil C18(250mm?4.6mm,5?m). The mobile phase consisted of acetonitrile-0.1% phosphate (6∶94) with flow rate of 1.0mL?min-1. The detection wavelength was 207nm and the column temperature was set at room temperature. RESULTS: The linear range of Ephedrine hydrochloride was 5.8～29.0?g (r=0.999 6), with average recovery at 98.13%,RSD=1.4%(n=9). CONCLUSION: This method was highly specific, sensitive and reproducible, and applicable for the quality control of Antiviral oral liquid.
