Study on the Extraction and Purification Process of Schisandrin
- VernacularTitle:五味子醇甲的提取纯化工艺研究
- Author:
Chenyi FAN
;
Huihua WEI
;
Yafang SHI
;
Yan CHEN
;
Xiaobin JIA
- Publication Type:Journal Article
- Keywords:
Orthogonal test;
Schisandrin;
Extraction process;
Purification
- From:
China Pharmacy
2001;0(12):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE: To optimize the process for extraction and purification of Schisandrin in Fructus Schisandra Chinensis. METHODS: The orthogonal test L9( 34) was adopted to optimize the water extraction process using Schisandrin and its extracts as indicators. The parallel test was used to optimize the parameters of the alcohol precipitation technique. RESULTS: The optimized process for extraction and purification of Schisandrin was as follows: extracting three times using 10- fold water, 1. 5h each time, with filter liquids concentrated to 1. 4g of crude drug mL- 1 then precipitated to 80% ; filtering alcohol liquids, and adjusting pH value to 7. CONCLUSIONS: This method can be used as a reference for the extraction of Fructus Schisandra Chinensis.
