Carbamazepine-induced Adverse Reactions:Clinical Characteristics and Related Factors
- VernacularTitle:卡马西平不良反应的临床特征及相关因素分析
- Author:
Zelian CHEN
;
Ting XU
;
Fengbo WU
;
Yao TANG
- Publication Type:Journal Article
- Keywords:
Carbamazepine;
Adverse drug reaction;
Clinical characteristics;
Related factors
- From:
China Pharmacy
2001;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To study the clinical characteristics and related of the adverse drug reactions(ADR) induced by carbamazepine,and propose preventive solutions.METHODS: 102 cases of carbamazepine-induced ADR,reported in medical journals of China from January 2001 to December 2005,were collected and analyzed.RESULTS:Skin and its appendages received most impairment from carbamazepine-induced adverse reactions(representing 35.3%),followed by general impairment of the body and impairment of the blood & hematopoietic system.Combined use of drugs is liable to induce adverse reactions,indicated by the fact that 16.7% of the sufferers received treatment by combined use of multiple drugs.Most of the ADR occurred 1h after administration.CONCLUSION:Individual differences of patients and combined use of drugs are among the factors that result in carbamazepine-induced adverse reactions.
