The Relationship between Serum Fibrinogen,Uric Acid and the Severity of Coronary Artery Diseases
- VernacularTitle:纤维蛋白原、血尿酸与冠心病严重程度的关系
- Author:
Mei MA
;
Xuemei GAO
;
Lihua HE
- Publication Type:Journal Article
- Keywords:
Fibrinogen;
Uric acid;
Coronary heart disease;
Logistic model;
Leaman scoring system
- From:
Chinese Journal of Prevention and Control of Chronic Diseases
2006;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study the relationship between serum fibrinogen,uric acid and the severity of coronary heart disease(CHD).Methods 156 patients with or without coronary heart disease were divided into CHD group and control group.All subjects were examined by cronary artery angiography.The severity of coronary artery stenosis was evaluated and graded with Leaman coronary scoring system.With the multiple analysis method,the relationships were studied between serum fibrinogen,uric acid and the severity of coronary heart disease.Results With multiple logistic regression,smoking,age,fibrinogen,triglyceride and low-density lipoprotein were independently associated with the severity of coronary heart disease.Gender,uric acid and other variables did not have significant independently association with the severity of coronary heart disease.With stepwise multiple regression analysis,age,fibrinogen,total cholesterol,lipoprotein(a)and low density cholesterol showed significant independent association with the severity of coronary heart disease,but uric acid and other variables did not.Conclusion Fibrinogen was related to the severity of coronary heart disease independently,but uric acid was not independently associated with the severity of coronary heart disease.
