Proliferation of Tet-on-LMP1 HNE2 Nasopharyngeal Carcinoma Cell Promoted by EB Virus LMP1
- VernacularTitle:EB病毒LMP1促进Tet-on-LMP1 HNE2鼻咽癌细胞增殖
- Author:
Xin SONG
;
Jianhua ZHANG
;
Zhimei SHANG
;
Yunchao HUANG
;
Zhimin LIU
;
Xueliang TANG
- Publication Type:Journal Article
- Keywords:
Latent membrane protein 1;
Cell cycle;
Proliferation
- From:
Journal of Kunming Medical University
1990;0(02):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the biological effects of EB encoding latent membrane protein 1(LMP1) on Tet-on-LMP1 HNE2 nasopharyngeal carcinoma cell line.Methods Proliferation of Tet-onLMP1 HNE2 cell induced by DOX at the different time points was detected by Western blot assay,DNA content assay,cell growth curves assay,colonogenesis assay in the soft agar and MTT colorimetric method.Results With the increasing LMP1 protein expression,Tet-on-LMP1 HNE2 progressed rapidly from G0/G1 to S phase,cells grew faster(P
