Activity of H~+-K~+-ATPase in gastric parietal cells under stress in rats and analysis of electron microscopic enzyme cytochemistry
- VernacularTitle:应激状态下大鼠胃壁细胞H~+-K~+-ATP酶活性测定及电镜酶细胞化学研究
- Author:
Yumei LI
;
Guoming LU
;
Xiaoping ZOU
;
Zhaoshen LI
;
Zhifang XIE
- Publication Type:Journal Article
- Keywords:
Stress;
Ulcer;
Parietal cells,gratric;
H+-K+-ATPase
- From:
Chinese Journal of Pathophysiology
1986;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To demonstrate the changes of activity and electron microscopic enzyme cytochemistry staining of H+-K+-ATPase of gastric parietal cells under stress in rats.METHODS: Twenty-four male SD rats were randomly divided into normal group,stress group and stress+omeprazole(OM) group.Water immersion-restraint stress(WRS) model in SD rats was performed.The ulcer index(UI) of gastric mucosa and H+-K+-ATPase activity of gastric parietal cells were measured.The changes of ultrastructure and electron microscopic enzyme cytochemistry staining of parietal cells were observed under transmission electron microscope(TEM).RESULTS: Compared with control group,the UI of gastric mucosa and H+-K+-ATPase activity of gastric parietal cells increased(P
