Study on the Water Extracts' Fingerprint of Ligusticum Chuanxiong Hort. Concomitant with Angelica Sinensis in Different Ratio
- VernacularTitle:不同比例川芎当归共煎液指纹图谱考察
- Author:
Jinchun SONG
- Publication Type:Journal Article
- Keywords:
Fingerprint;
HPLC;
Ferrulic acid;
Angelica sinensis;
Ligusticum chuanxiong Hort.;
Water extract
- From:
China Pharmacy
2001;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To study the fingerprint of Ligusticum chuanxiong Hort.concomitant with Angelica sinensis in different ratio boiled in water.METHODS:The gradient elution mode was applied in chromatographic separation.The stationary phase was Zorbax SB-C18(250mm? 4.6mm,5? m).The mobile phase consisted of methanol∶ water(containing 0.5% acetic acid).The UV detection was performed at 313 nm.RESULTS:No new substances were found in the water extracts of Li-gusticum chuanxiong Hort.concomitant with Angelica sinensis.Some ingredients released better when the two drugs boiled together with water.Ligusticum chuanxiong Hort.concomitant with Angelica sinensis at the ratio of 7∶ 3 had a bigger concentration of Ferrulic acid in water extract.CONCLUSION:The research provides the new way of R& D of cardiovascular drugs.
