Efficacy and Safety of Guaifenesin-Pseudoephedrine Hydrochloride-Codeine Phosphate Oral Solution
- VernacularTitle:愈酚伪麻待因口服溶液临床有效性和安全性评价
- Author:
Zhenglun XIAO
;
Jingping ZHENG
;
Jinfang MA
- Publication Type:Journal Article
- Keywords:
Guaifenesin-pseudoephedrine hydrochloride-odeine phosphate oral solution;
Compound codeine phosphate liquor;
Efficacy;
Safety
- From:
China Pharmacy
1991;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To evaluate the clinical efficacy and safety of guaifenesin,pseudoephedrine hydrochloride- codeine phosphate oral solution in relieving cough,eliminating phlegm,relieving nasal stuffiness and other cold symptoms. METHODS:A total of 240 patients with cold symptoms(120 cases in trial group and another 120 cases in control group) were enrolled in our multicenter,randomized,double-blinded and parallel controlled study and treated with guaifenesin-pseudoephedrine hydrochloride-codeine phosphate oral solutionI or compound codeine phosphate liquor 10mL tid for(5?2)d.RESULTS:227(112 in trial group and 115 in control group) were the valid cases with completed trial.Compared with pre-treatment,both of the 2 groups had a significant improvement in symptoms including cough,expectoration and nasal stuffiness after treatment(P
