Clinical Study of the Protective Effect of ACEI and ARB on Patients with Diabetic Nephropathy
- VernacularTitle:血管紧张素转换酶抑制剂和血管紧张素受体拮抗剂对糖尿病肾病患者肾功能的保护作用
- Author:
Xinxia HE
;
Weihong HAN
;
Yan XUE
- Publication Type:Journal Article
- Keywords:
Angiotensin converting enzyme inhibitor;
Angiotensin receptor antagonist;
Type 2 diabetic disease;
Diabetic nephropathy;
combination of therapy
- From:
Chinese Journal of Prevention and Control of Chronic Diseases
2006;0(01):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the protective effect of angiotensin converting enzyme inhibitor(ACEI) and angiotensin receptor antagonist(ARB) on renal function of type 2 diabetic nephropathy patients.Methods 60 patients with type 2 diabetic nephropathy and mild or midrange damages of renal function were observed.The patients all accepted routine diabetic therapy and were randomly divided into three groups,ACEI group,ARB group and combination group with ACEI and ARB.The blood pressure,blood creatinine and urine protein of 24 hours were measured before therapy and 8 weeks after therapy.Results The excretive amounts of urine protein decreased in all groups.The excretive levels of urine protein in combination group significantly decreased than in ACEI group and ARB group(P
