Detection of autoimmune antibody in patients with SLE after autologous hematopoietic stem cell transplantation
- VernacularTitle:系统性红斑狼疮患者自体造血干细胞移植后自身抗体的变化
- Author:
Jianhua LI
;
Jing SUN
;
Xuebiao PENG
;
Dan XU
;
Ledong SUN
;
Liang HUANG
;
Fanyi MENG
;
Jie ZHAO
;
Kang ZENG
- Publication Type:Journal Article
- Keywords:
Hematopoietic stem cell transplantation;
Systemic lupus erythematosus;
Autoimmune antibody
- From:
Journal of Chinese Physician
2002;0(S1):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To study changes of the autoimmune antibody level in patients after autologous hematopoietic stem cell transplantation(CD_(34)~+).Methods Twelve patients with SLE received autologous hematopoietic stem cell transplantation.All they survived and their immune system were recoverd after a period of time.The serum autoimmune antibody levels were measured before and after the transplantation,Results The antibody levels became normal 6 months after transplantation.Conclusion Autologous hematopoietic stem cell transplantation can effectively reduces the level of autoimmune antibody in patients with SLE.