Clinical research of T lymphocyte subgroup in patients with multiple sclerosis
- VernacularTitle:多发性硬化患者T淋巴细胞亚群与临床研究
- Author:
Liping WU
;
Shunxiu WU
;
Ming CHEN
;
Senmei LI
;
Xuan ZHENG
- Publication Type:Journal Article
- Keywords:
Multiple sclerosis T lymphocyte subgroup CSF
- From:
Journal of Chinese Physician
2002;0(S1):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore significance of the T lymphacyte subgroup in cases with multiple sclerosis(MS).Methods Indirect immunofluorescence assay and flow cytometry were used to evaluate the presence of CD_4~+,CD_8~+ and T lymphocyte in the sera and CSF in patients with MS treated with glucocorticoid in the active stage.Results The CD_4~+,CD_8~+ and T lymphocyte in the peripheral blood of the patients in comparison with those of the control group decreased whereas their CD_4~+/CD_8~+ increased(P