Clinical Observation of Polymorphous Light Eruption and Chronic Actinic Dermatitis Treated with Artemtherin
- VernacularTitle:蒿甲醚治疗多形性日光疹、慢性光化性皮炎的临床疗效观察
- Author:
Danqi DENG
;
Hao CHEN
;
Xiaohong ZHOU
;
Haiying LI
;
Hong XIE
;
Peilian ZHANG
- Publication Type:Journal Article
- Keywords:
Polymorphous light eruption;
Chronic actinic dermatitis;
Artemtherin;
Treatment
- From:
Journal of Kunming Medical University
2006;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To observe the clinical effect and safety of polymorphous light eruption(PLE) and those of chronic actinic dermatitis(CAD) treated with Artemtherin.To further study better treatment methods for photodermatitis.Methods 105 patients with CAD and 63 patients with PLE were divided into the treatment group and the control group randomly.In the treatment group,63 cases of CAD and 32 cases of PLE were treated with Artemtherin.In the control group,42 cases of CAD and 31 cases of PLE treated with Hydroxychlorquine.The dosages of both groups were 40 mg and 200 mg at each time,twice a day respectively.Both groups were topically treated with 10% ointment zinc oxide,twice a day,for one month.Results The effective rate of treatment group and control group with PLE patients were 84.4%(27/32) and 80.6%(25/31),respectively.There was no significant difference between both groups in terms of the effective rate of PLE.The effective rate of treatment group and control group with CAD patients were 85.7%(54/63) and 81%(34/4),respectively.There was not any side-effect reported among these patients treated with Artemtherin.Conclusions It is effective,safe,economic,and convenient to treat PLE and CAD with Artemtherin.
