Clinical study of microbial pathogens and drug susceptibility in appendical intracavity with appendicitis
- VernacularTitle:阑尾炎性疾病腔内菌群分类及药物敏感性临床研究
- Author:
Guanghui WANG
;
Xiangming CHE
;
Wei SHENG
;
Jiansheng ZHUO
;
Lin FAN
;
Wei ZHAO
;
Ruyuan ZHANG
- Publication Type:Journal Article
- Keywords:
Appendicitis;
Germiculture;
Detection rate;
Drug susceptibility
- From:
Chinese Journal of Postgraduates of Medicine
2006;0(35):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the pathogen and drug susceptibility in appendical intracavity with appendicitis, and guide clinically the selection of reasonable antibiotics. Methods Germicultures and drug susceptibility tests were conducted for the secretions from appendical intracavity of the 71 patients with appendicitis. Result (1) Totally 9 species (63 cases) of bacterium were isolated from clinical samples, positive rate of isolation was 88.7%. The first one was escherichia coli (49 cases). (2) The positive rates of germiculture were no differences in patients with different types of appendicitis. Age and BMI were associated with the results of germiculture. Gender, temperature, neutrophil, fecalith were not associated with the positive germiculture. (3) The curative effect of the third and the fourth generation cephalosporins and carbapenems were well. The curative effect of the first generation cephalosporins, quinolones and penicillins were not well. Conclusion (1)In all samples,escherichia coli are the dominant species of bacterium. The distribution of isolation is no difference in patients with different types of appendicitis. (2) The third generation cephalosporins are commonly used in clinical treatment with the obvious anti-bacteria effects, The fourth generation cephalosporins and carbapenems can act as the optimal drug for serious infection. Quinolones is not the optimal antibiotics. Penicillins antibiotic is not proposed to be used.
