Levels of adiponectin and their relation with insulin and tumor necrosis factor-? in cirrhosis
- VernacularTitle:肝硬化患者血清脂联素水平及其与胰岛素、肿瘤坏死因子-?的关系
- Author:
Yi TIAN
;
Jiansheng LIU
;
Jin LIU
;
Ji FU
;
Ming MA
;
Xiaohong ZHANG
- Publication Type:Journal Article
- Keywords:
Cirrhosis;
Adiponectin;
Insulin;
Tumor necrosis factor
- From:
Chinese Journal of Postgraduates of Medicine
2006;0(34):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the levels of adiponectin and the relation with insulin and tumor necrosis factor(TNF)- ? in patients with cirrhosis. Methods Adiponectin,insulin and TNF-? levels were determined in 73 patients with cirrhosis and 30 healthy controls, and were correlated with various clinical and biochemical parameters. Meanwhile Child-Pugh liver function was classified. Results Adiponectin was significantly elevated in patients with cirrhosis compared with the control. Adiponectin levels in cirrhosis was correlated positively with insulin and negatively with insulin sensitively index,and did not correlate with TNF-? and liver function.Conclusion Serum adiponectin levels in cirrhosis are significantly elevated. Adiponectin levels do not correlate with TNF-? and liver function, but exclusively insulin and insulin sensitivity index.
