Methylprednisolone pulse therapy of hematological disorders in systemic lupus erythematosus
- VernacularTitle:甲泼尼松龙治疗系统性红斑狼疮血液系统损害的临床观察
- Author:
Jihong YANG
;
Xuewen WANG
;
Yaping YU
;
Yongping ZHAI
;
Haining LIU
- Publication Type:Journal Article
- Keywords:
Systemic lupus erythematosus;
Hemocytopenia;
Methylprednisolone
- From:
Chinese Journal of Postgraduates of Medicine
2006;0(34):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To explore methylprednisolone and conventional dose prednisone treatment for hematological damage in systemic lupus erythematosus(SLE) in the near future response. Methods Hemocytopenia in 147 patients with SLE were treated by intravenous injecting methylprednisolone and conventional dose prednisone and therapy response were observed in the tenth day after treatment. Results The responses were obtained in methylprednisolone and in conventional dose prednisone increased percentage of Hb were 34.8% and 14.0%,of WBC were 76.7% and 63.0%,of Pt were 66.7% and 27.3% in two group respectively. In comparison of values of Hb,WBC,and Pt before treatment with those after treatment showed significant difference in two groups(P
