Significance of detection of platelet membrane glucoprotein and platelet aggregation function in diabetes mellitus patients with retinopathy
- VernacularTitle:糖尿病视网膜病变血小板膜糖蛋白及血小板聚集功能的检测意义
- Author:
Ankui JIA
- Publication Type:Journal Article
- Keywords:
Diabetic retinopathy;
Platelet membrane glycoproteins;
Lysosmes;
Platelet aggregation
- From:
International Journal of Laboratory Medicine
2006;0(11):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the change of platelet membrane glucoprotein CD62p,CD63 expression and platelet aggregation function in diabetes mellitus patients with retinopathy. Me-thods Platelet membrane glucoprotein CD62p and CD63 expression were analyzed by flow cytometry(FCM)and their adenosine diphosphate (ADP)-induced platelet aggregation function was determined in diabetes mellitus patients with retinopathy,and compared with those of diabetes mellitus patients without vascular disease,and normal controls.Results The positive rates of CD62p,CD63 and the rate of platelet aggregation function in diabetes mellitus patients with retinopathy were(8.74?3.01),( 9.38?3.25)and(58.9?9.7),significantly higher than those in normal controls 2.89?1.72(P
