Study on Antipyretic and Analgesic Effects of Compound Tuniuxi Sirup
- VernacularTitle:复方土牛膝糖浆解热、镇痛作用研究
- Author:
Quanxi MEI
;
Xiwen ZHONG
;
Ying HU
;
Yuqiao GAO
;
Ting LIU
;
Hui LIN
;
Huifei WU
- Publication Type:Journal Article
- Keywords:
Componnd tuniuxi sirup;
Antipyretic;
Rat;
Analgesia effect;
Mice
- From:
China Pharmacy
2005;0(22):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To study the antipyretic and analgesic effects of Compound tuniuxi sirup.METHODS:Fever was induced by dry yeast in SD rats,then divided the rats into high-dose(33.12g/kg),medium-dose(16.56g/kg),low-dose(8.28g/kg)and control,aspirin group,observed the antipyretic effect;The mice were divided into high-dose(47.84g/kg),medium-dose(23.92g/kg),low-dose(11.96g/kg)and control,aspirin group,then were investigated with hot plate and acetic acid induced body twist.RESULTS:Compound tuniuxi sirup can markedly inhibit the fever in the model anmals 1 hour later,the effect of the high,medium groups are similar to aspirin;and could increase the pain threshold obviously(the low-dose group is obviously in 1.5h~2h(P