Preparation and Stability of Xiaocuo Emulsion
- VernacularTitle:消痤乳的制备及稳定性考察
- Author:
Dongmei YE
;
Shun LAN
;
Shengfang JIN
- Publication Type:Journal Article
- Keywords:
Xiaocuo emulsion;
Preparation;
Azone;
Tween-80;
Stability
- From:
China Pharmacy
2005;0(22):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To prepare Xiaocuo emulsion and to study its stability.METHODS:The formula and techniques were optimized with metronidazuo,cimetidine,chloramphenicol and salicylic acid as the chief ingredients,and with the uniformity of emulsion as the indicator.The stability test was performed using storage test and accelerated centrifugal test.RESULTS:The optimized formula was the following,5ml azone,4ml tween-80,1g metronidazole,2g cimetidine,2g chloramphenicol,1g salicylic acid and 100ml deionized water.CONCLUSION:The preparation is reasonable in formula,simple in preparative techniques,stable in quality and feasible in production.
