Effect of atorvastatin on intima media thickness of the carotid artery in transient ischemic attack patients with normal cholesterol
- VernacularTitle:阿托伐他汀对血脂正常的短暂性脑缺血发作患者颈动脉内膜-中层厚度的影响
- Author:
Guoyan XU
;
Ling CHEN
;
Kegui WU
;
Cuilin CHEN
;
Zhongxin WANG
;
Xiangjun ZENG
- Publication Type:Journal Article
- Keywords:
Transient ischemic attack;
Carotid artery;
Intima media thickness;
Atorvastatin
- From:
Chinese Journal of Postgraduates of Medicine
2006;0(31):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate if atorvastatin is effective in reducing carotid intima media thickness (CA-IMT) in normocholesterolaemic patients with transient ischemic attack (TIA). Methods Forty-two patients with TIA were recruited. Patients were randomised to receive atorvastatin(5-10 mg/d) or placebo daily. Serum concentration of cholesterol and CA-IMT were measured before randomisation and at 6-and 18-month intervals. Results CA-IMT was significantly lower in atorvastatin group than that in placebo group at 18-month (P
