Shenfu Injection in Combination with Rougui in the Treatment of Oxaliplatin-induced Neurotoxicity
- VernacularTitle:参附注射液联合肉桂防治奥沙利铂神经毒性疗效观察
- Author:
Tingrong ZHANG
;
Chen XU
;
Weisheng SHEN
;
Yao ZHANG
;
Ye LU
- Publication Type:Journal Article
- Keywords:
Shenfu injection;
Rougui;
Oxaliplatin;
Neurotoxicity
- From:
China Pharmacy
2005;0(20):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To observe the therapeutic effect of Shenfu Injection in combination of rougui for oxaliplatin-induced neurotoxicity.METHODS:A total of 73 cases with malignant tumor were randomly divided into control group and treatment group:the control group was treated with chemotherapy alone,in which oxaliplatin was included;the treatment group was treated intravenously with Shenfu Injection 40～60ml for 7～10d plus orally with 3g Rougui decoction prior to chemothera_py.RESULTS:Incidences of neurotoxicity for the treatment group and the control group were 13.5% and 55.6%,respectively.Significant differences were noted between 2 groups(P
