The Effects of Transient Intensive Insulin Treatment on Beta-cell Function in Newly Diagnosed Type II Diabetic Patients
- VernacularTitle:胰岛素强化治疗对初诊2型糖尿病患者胰岛?细胞功能的影响
- Author:
Hongmei QIU
;
Guoqing SHEN
;
Kaiping LIU
;
Wei LI
;
Xiaofang ZHOU
;
Jiyu YIAO
- Publication Type:Journal Article
- Keywords:
Type II diabetes mellitus;
Insulin;
Intensive treatment;
Pancreatic beta cells
- From:
Journal of Kunming Medical University
2006;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
11.1 mmol/L were treated by 2 weeks CSII.An intravenous glucose tolerance test(IVGTT) was performed before and after CSII.The levels of fasting plasma glucose(FPG),2 hours postprandial glucose(2hPG),glycosylated hemoglobin A1c(HbA1c),first-phase secretion of insulin,the mean area under the curve(AUC) of insulin,insulin sensitivity index(ISI),insulin resistance index(Homa IR) and insulin secretion index(Homa ?) were compared.Results The excellent control of FPG and 2hPG in 20 out of 21 patients were achieved stably in 2.8?1.6 days and 7.8?1.9 days by CSII.After the treatment,FPG,2h PG and HbA1c were significantly decreased(P
