The management of biliary complications in orthotopic liver transplantation recipients with hepatic artery stricture
- VernacularTitle:肝移植术后肝动脉狭窄患者胆管并发症的治疗
- Author:
Genshu WANG
;
Guihua CHEN
;
Minqiang LU
;
Yang YANG
;
Changjie CAI
;
Huimin YI
;
Hua LI
;
Chi XU
;
Shuhong YI
;
Hong SHAN
;
Zaibo JIANG
- Publication Type:Journal Article
- Keywords:
Liver transplantation;
Hepatic artery stricture;
Biliary complications
- From:
Chinese Journal of General Surgery
2001;0(10):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the role of hepatic artery interventional therapy for the prevention and treatment of biliary complications in orthotopic liver transplantation(OLT) with hepatic artery stricture (HAS). Methods We retrospectively analyzed biliary complications of 22 OLT recipients with HAS from Oct 2003 to Mar 2006 and evaluated the role of hepatic artery interventional therapy. Results One of three OLT recipients receiving early retrieval second transplants died of severe infection. The remaining 18 recipients were complicated with elevated?-glutamyl transferase and alkaline phosphatase, among them eleven (61. 1%) developed biliary stricture(BS) ,1(5. 6%) suffered from biliary leakage. Six (50%) of the 12 patients receiving hepatic artery interventional therapy developed BS later which was ameliorated by biliary interventional treatment. One of 2 patients receiving no hepatic artery interventional therapy developed BS which was cured by conservative treatment. None of the 4 patients receiving hepatic artery interventional therapy after the establishment of BS was cured and 3 (3/4) were improved and 1 (1/4) continued to deteriorate after hepatic artery and biliary interventional treatment. Conclusions Patients with HAS after OLT have a high rate of biliary complications. The result of hepatic artery interventional therapy to prevent and treat biliary complications of the patients with HAS is not satisfactory.
