Compound Glycyrrhizin in the Prevention of Liver Injury Induced by Antituberculosis Drugs
- VernacularTitle:复方甘草酸苷预防抗结核药物致肝损伤的疗效观察
- Author:
Yonghua ZHAO
;
Jianwu YU
;
Jie GAO
;
Peng KANG
;
Ming LIANG
;
Shuchen LI
- Publication Type:Journal Article
- Keywords:
Compound glycyrrhizin;
Antituberculosis;
Liver injury;
Observation of curative effects
- From:
China Pharmacy
2005;0(19):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE: To evaluate the efficacy of compound glycyrrhizin in preventing liver injury induced by antituberculosis drugs. METHODS: A total of 180 cases with pulmonary tuberculosis were randomly divided into control group and trial group: 90 cases in the control group were treated with antituberculosis drugs alone for 6～8 months,and another 90 cases in the trial group were treated concomitantly with antituberculosis drugs and compound glycyrrhizin,the incidences of liver injury between 2 groups were monitored. RESULTS: The incidences of liver injury of the control group and the trial group were 32.2% and 8.9%,respectively(P
