Production and Activity of Serum Neutralizing Antibody in Different Animals Undergoing Long-term Toxicity Study with Recombinant Consensus Interferon ?
- VernacularTitle:重组集成干扰素?在不同动物长期毒性实验血清中中和抗体的产生及活性研究
- Author:
Bing XU
;
Dai LI
;
Xiaoling ZHAN
;
Jinhua LIU
;
Yanghua XU
- Publication Type:Journal Article
- Keywords:
Recombinant consensus interferon ?;
Cytopathic-effect inhibition assay;
Hamsters;
Rhesus monkeys;
Neutralizing antibody;
Antibody activity
- From:
China Pharmacy
2005;0(18):-
- CountryChina
- Language:Chinese
-
Abstract:
0.05).In1?g/kg dosage group,no neutralizing activity was detected at the end of convalescent period.CONCLUSION:The neutralizing antibodies can be detected in the serum of both hamsters and rhesus monkeys after repeating injection of recombinant consensus interferon?.The titers of antibody are in direct ratio with the duration and the injected dose.
