Study of traditional Chinese medicine combined with regular therapy in the treatment of pneumonia with systemic inflammatory response syndrome in children
- VernacularTitle:中药协同治疗小儿肺炎合并全身炎症反应综合征的机制研究
- Author:
Feng YU
;
Minxian CUI
;
Jincheng HUANG
;
Jiangbo XIONG
;
Dongli YAO
;
Feijin LIN
- Publication Type:Journal Article
- Keywords:
pneumonia;
systemic inflammatory response syndrome;
inflammatory cytokin;
traditional Chinese medcine
- From:
Chinese Journal of Integrated Traditional and Western Medicine in Intensive and Critical Care
2006;0(05):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To explore the mechanism of traditional Chinese medicine(TCM) combined with regular therapy in the treatment of pneumonia with systemic inflammatory response syndrome(SIRS) in(children).Methods: Sixty-four children with pneumonia including 51 cases with SIRS complication were(randomly) divided into three groups: treatment group(regular therapy+TCM,n=26),control group Ⅰ((regular)(therapy) only,n=25) and the control groups Ⅱ(13 pneumonia children without SIRS(receiving)(routine) treatment). The dynamic changes of tumor necrosis factor-?(TNF-?),interleukin-6(IL-6) and IL-8 were measured before and after treatment in all children.Serum Creactive protein(CRP) and total white blood cell(WBC) count were measured simultaneously.Clinical symptom and sign scores were(performed)(5 days) after treatment in children with pneumonia and SIRS complication.Results: Before(treatment),serum TNF-?,IL-6,IL-8 and CRP concentrations were significantly higher in treatment group and(control) group Ⅰ than(control) group Ⅱ(all P
