Diagnosis and surgical treatment of parathyroid carcinoma
- VernacularTitle:甲状旁腺癌的诊断和治疗
- Author:
Xi CHEN
;
Weiyao CAI
;
Yanggang HE
;
Guang NING
;
Jianmin LIU
;
Wenqiang FANG
;
Xiaolong JIN
;
Hongwei LI
- Publication Type:Journal Article
- Keywords:
Parathyroid neoplasms;
Diagnosis;
Surgical procedure, operative
- From:
Chinese Journal of General Surgery
2001;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the diagnosis and surgical treatment of parathyroid carcinoma (PTC). Methods Clinical data of 8 PTC cases were analyzed retrospectively. Results PTC accounted for 5. 7% of patients with primary hyperparathyroidism (PHPT) in our hospital. There were 4 men and 4 women. Male patients had younger mean onset age compared with female patients. The disease history of PTC was shorter than PHPT of benign causes. Six patients were admitted for acute hypercalcemia. Seven patients complained of palpable neck mass. Calcium level was 3.75?0.34 mmol/L,and PTH level was 1429.47?841.75 pg/ml. Frozen section established diagnosis in only one case. Four patients underwent radical en bloc resection. Other 4 cases received routine simple parathyroidectomy, 3 patients developed recurrence in 12 - 18 months postoperatively. Conclusions Acute hypercalcemia is common in PTC. Frozen biopsy diagnosis is not satisfactory. An initial en bloc resection of tumor and adjacent structures contributes most to the prognosis.
