The influence of insulin resistance and insulin secretion in women with glucose intolerance during late pregnancy
- VernacularTitle:胰岛素抵抗与胰岛素分泌在妊娠期糖代谢异常发病中的作用
- Author:
Yuzhu YIN
;
Jianhui FAN
;
Xiaowei CHEN
;
Hongying HOU
;
Baiquan JIANG
- Publication Type:Journal Article
- Keywords:
Insulin resistance;
Insulin;
Diabetes,gestational;
Glucose metabolism disorders
- From:
Journal of Chinese Physician
2001;0(09):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the relationship of insulin resistance and secretion during late pregnancy in women with glucose intolerance.Methods Immunoenzymetric assay was used to measure the fasting serum insulin levels in 122 pregnant women which including of 36 pregnant women with gestational diabetes mellitus(GDM),34 pregnant women with gestational impaired glucose tolerance(GIGT),and 52 pregnant women with normal glucose tolerance(NGT).The fasting plasma glucose levels were measured by glucose oxidase method.The insulin sensitivity index(ISI) and islet secretive function index(IFI) were compared between the three groups.Results ISI had an increasing trend from NGT group,GIGT group to GDM group(P
