Implantation of ~(125)I Particles plus5-FU Slow-release Particles for Advanced Pancreatic Cancer
- VernacularTitle:~(125)I粒子联合5-氟尿嘧啶缓释化疗粒子植入治疗晚期胰腺癌疗效观察
- Author:
Longbin MA
;
Bin LI
;
Jin HE
;
Xinyuan WANG
;
Dawei ZHANG
;
Jianhui GAN
;
Xizhu WANG
- Publication Type:Journal Article
- Keywords:
125 I particles;
5-FU slow-release chemotherapeutic particles;
Pancreatic cancer;
Curative effect
- From:
China Pharmacy
2005;0(16):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To observe the clinical effects of interstitial implantation of 125 I particles together with5-FU slow-release particles for advanced pancreatic cancer.METHODS:A total of12patients with advanced pancreatic cancer whose tumors were unsuitable to be resected were implanted with5-FU slow-releasing particles and then 125 I particles.The intensity of radioactive 125 I particles was0.4mCi～0.5mCi,the matched peripheral dose was60Gy～100Gy,and an average of16 125 I particles and1000mg5-FU were used for each patient.RESULTS:Relief of pain was achieved in all the subjects,with the effective rates of odynolysis at91.7%.The tumor size in all the subjects was diminished to some degree,with local control rate at83.3%.1y survival rate was25%.CONCLUSION:Interstitial implantation of 125 I particles and5-FU slow-release particles for advanced pancreatic cancer is simple,safe and effective.
