Correlated Study of Heroin Dependence and Mu Opioid Receptor Gene
- VernacularTitle:海洛因依赖与?阿片受体基因多态性的关联研究
- Author:
Zhou DU
- Publication Type:Journal Article
- Keywords:
Heroin dependence;
Mu opioid receptor gene;
Polymorphism
- From:
Journal of Kunming Medical University
1986;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To detect relation between heroin dependence and mu opioid receptor gene.Methods Genotype and allele frequencies of polymorphisms of mu opioid receptor gene was examined in 313 heroin-dependence subjects and 214 normal controls.Results No difference in genotype and allele frequencies of polymorphism of mu opioid receptor gene were observed between heroin-dependent subjects and normal controls(?~2=3.73,P=0.16 and.?~2=0.76,P=0.38).Conclusion The results suggested that polymorphism of mu opioid receptor gene was not associated with heroin dependence.