Content Determination of Naproxen in Naproxen-?-cyclodextrin Inclusion Complex by UV Spectropho-tometry
- VernacularTitle:紫外分光光度法测定萘普生-?-环糊精包合物中萘普生的含量
- Author:
Guoping ZHAN
;
Daoli PAN
- Publication Type:Journal Article
- Keywords:
UV spectrophotometry;
Naproxen-?-cyclodextrin inclusion complex;
Naproxen;
Content determination
- From:
China Pharmacy
2005;0(15):-
- CountryChina
- Language:Chinese
-
Abstract:
OBJECTIVE:To establish a method for the content determination of naproxen in naproxen-?-cyclodextrin inclusion complex.METHODS:The drug concentration in naproxen-?-cyclodextrin inclusion complex was detected at the wavelength of330nm by using UV spectrophotometry.RESULTS:The linear range of naproxen was2.0～80.0mg/L(r=0.9995,n=5),the average recovery was99.22%(RSD=1.03%).CONCLUSIONS:The method is simple and reliable,which can be used for the content determination of naproxen in naproxen-?-cyclodextrin inclusion complex.
