Effect of Tongxinluo capsule (通心络胶囊) on microcirculatory changes of nail bed and hemorrheology in patients with coronary artery disease and angina pectoris
- VernacularTitle:通心络胶囊对冠心病心绞痛甲襞微循环和血液流变学变化的影响
- Author:
Surong ZHANG
;
Zhigang CHEN
;
Fenghua LU
;
Yongchun ZHANG
;
Hongjun LI
;
Yu YUAN
;
Luli HUANG
;
Weiguo ZHANG
- Publication Type:Journal Article
- Keywords:
Tongxinluo capsule;
coronary heart disease;
angina pectoris;
microcirculation of nail bed;
hemorrheology
- From:
Chinese Journal of Integrated Traditional and Western Medicine in Intensive and Critical Care
2006;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective: To investigate the mechanisms of curative effect of Tongxinluo capsule(通心络胶囊) on patients with coronary artery disease and angina pectoris.Methods: One hundred and twelve cases in accord with the diagnostic criteria of coronary heart disease of World Health Organization(WHO) were(randomly) divided into two groups: treatment group(n=60) and control group(n=52).The patients in both groups were treated with routine therapy including ?receptor retardant and ester of nitric acid etc.(Additionally),the treatment group was treated with Tongxinluo capsules,2 capsules each time and 2 times(per day) for 2 months consecutively.The clinical manifestations before and after treatment,the changes of(electrocardiogram)(ECG),microcirculation of nail bed and hemorrheology were observed in all the patients in both groups.Results: The total clinical effective rate and the rate of total improvement in ECG changes were 86.67% and 80.00% respectively after treatment in the treatment group,and compared with the control group(78.85% and 69.23%) the differences were significant(both P
