Diagnosis and treatment of thyroid Hurthle cell neoplasms
- VernacularTitle:46例甲状腺Hurthle细胞肿瘤的诊断与治疗
- Author:
Weiliang YANG
;
Dongwei ZHANG
;
Huadong QIN
;
Haomin ZHANG
;
Zhi ZHAO
;
Jianguo ZHANG
;
Jianhua PEI
;
Cheng ZHANG
- Publication Type:Journal Article
- Keywords:
Thyroid neoplasms;
Adenoma, oxyphilic;
Diagnosis;
Surgical procedures, operative
- From:
Chinese Journal of General Surgery
2001;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To summarize our experience in the diagnosis and treatment of thyroid Hurthle cell neoplasms. Methods Clinical data of thyroid Hurthle cell neoplasm patients admitted from 1972 to 2003 were analyzed retrospectively. Results The main symptoms were thyroid solitary node or mass (37 cases) and multiple nodule (9 cases). 4 cases had cervical lymph node metastasis. With BUS、CT、ECT and FNAC,only 10 cases were diagnosed as HCNs preoperatively, 36 cases were misdiagnosed as nodular benign single or multiple node. Twenty-eight cases were diagnosed by FNAC and quick freezing pathology. Benign HCNs was treated by isolateral thyroidectomy and malignant HCNs by additional contralateral subtotal thyroidectomy. Eighteen cases were diagnosed by postoperative paraffin pathology, and retrival second operation was performed according to the benignity or malignancy of the thyroid lesion. All cases were followed-up for 2 to 10 years and doing well without recurrence. Conclusions We should realize thyroid Hurthle cell neoplasms fully, if HCNs is suspected intraoperatively, quick freezing pathology is helpful. With appropriate therapy, the prognosis is satisfactory.
