Maternal antepartum fever and early-onset bacterial sepsis in neonates in Shanghai
- VernacularTitle:上海市母产前发热与早期新生儿败血症临床多中心研究
- Author:
Xuhong WANG
;
Yuehua SHEN
;
Yongmei HUANG
- Publication Type:Journal Article
- Keywords:
Pregnancy complications,infectious;
Fever;
Infant,newborn;
Septicemia
- From:
Chinese Journal of Perinatal Medicine
2000;0(04):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To evaluate the relationship between maternal antepartum fever and early-onset neonatal bacterial sepsis.Methods A retrospective multi-centred clinical study of 404 neonates including 103 new borns with maternal antepartum fever and 311 neonates without was conducted.Results The frequency of early-onset neonatal bacterial sepsis was significantly higher in neonate with maternal antepartum fever than those without(4.9% vs 0.3%,P=0.001).Both maternal antepartum temperature ≥39℃ and maternal postpartum fever lasting several days was higher suggested the possibility of neonatal sepsis.Conclusions The neonates born with high risk factor of early-onset neonate bacterial sepsis require comprehensive lab evaluation including blood culture and uterine culture,clinical observation and aggressive treatment to decrease the mortality.
