The model of rapid-harvesting donor liver in rat orthotopic liver transplantation
- VernacularTitle:供肝快速切取法大鼠原位肝移植模型的建立
- Author:
Jun LI
;
Kefeng DOU
;
Hongtao ZHANG
;
Fuqin ZHANG
;
Yalin KONG
;
Qingchuan ZHAO
- Publication Type:Journal Article
- Keywords:
Liver Tansplantation;
Models,Animal;
Rapid Harvesting Donor
- From:
Chinese Journal of General Surgery
2001;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To develop a rapid donor liver harvesting method in orthotopic liver transplantation in rats,and to study the stability and the success rate of the model.Methods A total of 200 healthy adult male SD rats were randomly divided into two groups: the experimental group(rapid donor liver harvesting transplant group),and the control group(conventional liver transplant group).The operation time,cold(ischemic) time and warm ischemic time of the donor liver, recipient post-transplation liver function and the success rate of the operation between the 2 grous were cpmpared.Results In the control group,the(operation) time of donor harvesting was(33.8?4.2) min,warm ischemic time and cold ischemic time of donor liver was(3.5?1.2) min and(62.0?4.2) min,with a 80% rate of success.The new method reduced the time for donor surgery to(13.1?2.2)min,and reduced the warm ischemic time and cold(ischemic) time of donor liver to 0 min and(38.0?3.1)min respectively,and with a 94% rate of success(all P
