Effects of liver transplantation on function and morphological changes of spleen in hepatic cirrhosis rat
- VernacularTitle:肝移植对肝硬化大鼠脾功能及脾组织形态学的影响
- Author:
Chen HUANG
;
Zhengjun QIU
;
Fang ZHANG
;
Yi TAN
;
Yong GAO
;
Jinxin LIU
- Publication Type:Journal Article
- Keywords:
Liver Transplatation;
Hepatic Cirrhosis;
Spleen/physipathol;
Spleen/pathol
- From:
Chinese Journal of General Surgery
2001;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the effects of liver transplantation on function and morphological changes of spleen in hepatic cirrhosis rats.Methods Hepatic cirrhosis model was established in rats by subcutaneous injections of carbon tetrachloride.Liver transplantation model was established with two-cuff technique.The portal vein pressure,and morphological changes of spleen were observed before and after liver transplantation in hepatic cirrhosis rats.The serum tuftsin level before and after liver transplantation were detected.Results Before liver transplantation,PVP was increased from 6.28 mmHg to 14.03mmHg(P
