The expression of angiopoietin 2 gene in glioma and its relationship with angiogenesis
- VernacularTitle:胶质瘤促血管生成素2基因表达与血管生成关系的实验研究
- Author:
Wangchi LUO
;
Songsheng SHI
;
Weizhong YANG
;
Chunmei CHEN
- Publication Type:Journal Article
- Keywords:
Glioma;
Angiopoietin-2
- From:
Journal of Chinese Physician
2001;0(07):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To investigate the expression of angiopoietin 2 gene in glioma and its relationship with angiogenesis.Methods The expression of angiopoietin 2 were examined by RT-PCR in 52 cases of glioma and 8 normal brain tissues.The vascular development was measured by microvessel count(MVC) which was immunostained with anti-CD34 monoclonal antibody.Results The expression of ang2 mRNA was found in 50 cases of gliomas and 8 normal brain tissues,and the expression of ang2 mRNA was significantly positively correlated with MVC(r=0.821,P
