Experimental Model of Acute Myocardial Infarction Induced by Ligation of Coronary Artery in Swines
- VernacularTitle:开胸结扎猪冠状动脉建立急性心肌梗死动物模型的研究
- Author:
Lin SUN
;
Guochang XIONG
;
Xuefeng GUANG
;
Yi LI
;
Zhimin RUAN
;
Fen YANG
- Publication Type:Journal Article
- Keywords:
Myocardial infarction;
Experimental animal model;
Swine
- From:
Journal of Kunming Medical University
1988;0(03):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective To establish an experimental animal model of acute myocardial infarction (AMI) in the swine. Methods Under sterilization, the swine’s chest was cut open and the left circumflex coronary artery (LCX) was ligated.Results After the operation, the changes of Electrocardiogram (ECG) and myocardial-enzymes in the blood serum and selective coronary angiography all proved that the animal model of AMI in the swine was successful. Conclusions Ligating coronary was a valuable method to make an animal model of AMI.