Relationship between Hepatitis B Virus Variation and TCM Syndrome Types in HBeAg-Negative Patients of Chronic Hepatitis B
- VernacularTitle:慢性乙型肝炎HBeAg阴性患者乙肝病毒变异与中医辨证分型的关系
- Author:
Qian XIAO
- Publication Type:Journal Article
- Keywords:
Hepatitis,type B/diagnosis;
TCM syndrome classification;
Hepatitis virus,type B/genetics
- From:
Journal of Traditional Chinese Medicine
1993;0(06):-
- CountryChina
- Language:Chinese
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Abstract:
Objective:To probe the relationship between hepatitis B virus(HBV) variation and TCM syndrome types in HBeAg-negative patient of chronic hepatitis B.Methods:Eighty-four cases of HBeAg-negative patient of chronic hepatitis B were divided into 5 syndrome types according to TCM differentiation.C gene promoter (BCP area) and pre-C gene termination variation in HBV were detected with gene chip for HBV mutation detection.Results:There was no significant correlativity between generation of HBV variation and TCM syndrome types in HBeAg-negative patient of hepatitis B as compared with HBeAg-positive patient;The variation rate of the BCP area and/or the pre-C area was 34.5% in prevailing excess syndrome group and 65.5% in the prevailing deficiency group,the former being higher than the latter.Conclusion:There is correlativity between variation of BCP area and/or pre-C area and TCM syndrome types,with the variation rate of the excess syndrome being lower than that of the deficiency syndrome.
