Effects of Fuzheng Huoxue Recipe on Blood Growth Hormone and Insulin Growth Factor in Chronic Renal Failure Rats
- VernacularTitle:扶正活血方对慢性肾功能衰竭大鼠血生长激素和胰岛素生长因子的影响
- Author:
Jun LI
;
Liqun HE
;
Yi LI
- Publication Type:Journal Article
- Keywords:
Renal failure,chronic/TCM therapy;
Growth-regulating hormones/drug action;
@ Fuzheng Huoxue Recipe
- From:
Journal of Traditional Chinese Medicine
1993;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
Objective:To observe effects of Fuzheng Huoxue Recipe on blood growth hormone (GH) and insulin growth factor(IGF-1) in chronic renal failure(CRF) rats.Methods:Platt method was adopted to make 5/6 kidney excision CRF model rat,and the rats were divided into model group,Huangqi group,Enalapril group,Danshen group,Fuzheng Huoxue Recipe group and normal control group according to the blood creatinine level after modeling.Effects of Fuzheng Huoxue Recipe on GH and IGF-1 levels in CRF rats with large quantity of urinal protein were investigated.Results:GH and IGF-1 levels in the model control group were significantly higher than that in normal control group,and after treatment of Fuzheng Huoxue Recipe,blood GH and IGF-1 levels were significantly decreased.Conclusion:Fuzheng Huoxue Recipe can decrease blood GH and IGF-1 levels in CRF rats,and can delay advances of CRF.
