Type and cause of liver disease in Korea: single-center experience, 2005-2010.
10.3350/cmh.2012.18.3.309
- Author:
Sang Soo LEE
1
;
Young Sang BYOUN
;
Sook Hyang JEONG
;
Yeo Myung KIM
;
Ho GIL
;
Bo Young MIN
;
Mun Hyuk SEONG
;
Eun Sun JANG
;
Jin Wook KIM
Author Information
1. Department of Internal Medicine, Seoul National University Bundang Hospital, Seoul National University College of Medicine, Seongnam, Korea. jsh@snubh.org
- Publication Type:Original Article
- Keywords:
Liver disease;
Diagnosis;
Etiology, Korea
- MeSH:
Acute Disease;
Adolescent;
Adult;
Aged;
Aged, 80 and over;
Alcohol Drinking/adverse effects;
Carcinoma, Hepatocellular/epidemiology/etiology/pathology;
Chronic Disease;
Cohort Studies;
Fatty Liver/epidemiology;
Female;
Hepatitis/epidemiology;
Hepatitis, Viral, Human/complications/epidemiology;
Humans;
Liver Cirrhosis/epidemiology/etiology;
Liver Diseases/*diagnosis/epidemiology;
Liver Diseases, Alcoholic/complications/epidemiology;
Liver Neoplasms/epidemiology/etiology/pathology;
Male;
Middle Aged;
Prevalence;
Republic of Korea/epidemiology;
Retrospective Studies;
Young Adult
- From:Clinical and Molecular Hepatology
2012;18(3):309-315
- CountryRepublic of Korea
- Language:English
-
Abstract:
BACKGROUND/AIMS: The aim of this study was to describe the types and causes of liver disease in patients from a single community hospital in Korea between April 2005 and May 2010. METHODS: A cohort of patients who visited the liver clinic of the hospital during the aforementioned time period were consecutively enrolled (n=6,307). Consistent diagnostic criteria for each liver disease were set by a single, experienced hepatologist, and the diagnosis of all of the enrolled patients was confirmed by retrospective review of their medical records. RESULTS: Among the 6,307 patients, 528 (8.4%) were classified as acute hepatitis, 3,957 (62.7%) as chronic hepatitis, 767 (12.2%) as liver cirrhosis, 509 (8.1%) as primary liver cancer, and 546 (8.7%) as a benign liver mass or other diseases. The etiologies in the acute hepatitis group in decreasing order of prevalence were hepatitis A (44.3%), toxic hepatitis (32.4%), other hepatitis viruses (13.8%), and cryptogenic hepatitis (9.1%). In the chronic hepatitis group, 51.2% of cases were attributed to viral hepatitis, 33.3% to nonalcoholic fatty liver disease, and 13.0% to alcoholic liver disease (ALD). Of the cirrhoses, 73.4% were attributable to viral causes and 18.1% to alcohol. Of the hepatocellular carcinoma cases, 86.6% were attributed to viral hepatitis and 11.6% to ALD. Among the benign tumors, hemangioma comprised 52.2% and cystic liver disease comprised 33.7%. CONCLUSIONS: Knowledge of the current status of the type and cause of liver disease in Korea may be valuable as a basis for evaluating changing trends in liver disease in that country.
