Effect of huayu xiaoliu fang on cell cycle of a human lung carcinoma cell line
- VernacularTitle:化瘀消瘤方含药血清对体外培养的人肺癌细胞周期的影响
- Author:
Tingxiu ZHAO
;
Jiangfeng YOU
;
Zhenfa CHEN
;
Xingfan QIU
;
Jing HU
;
Xiang XU
;
Xiulian WANG
;
Min HUANG
;
Xiaoguo HU
- Publication Type:Journal Article
- Keywords:
Huayu Xiao Liu Fang;
Cell cycle;
Lung neoplasms
- From:
Chinese Journal of Pathophysiology
1989;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To investigate the effect of huayu xiaoliu fang, a Chinese medicine, on the cell cycle of human lung carcinoma cell line by serologic pharmacological method. METHODS: PGLH7 cells were incubated with rabbit serum containing huayu xiaoliu fang at different doses obtained by serologic pharmacological method. MTT assay was used to calculate the proliferation inhibition rate. The target cells were harvested to analyze the cell cycles by flow cytometry. RESULTS: The Chinese medicine-containing serum inhibited the growth of PGLH7 cells significantly. There was remarkable difference in the proliferation inhibition rate between 10% (high dose) Chinese medicine-containing serum and the control serum (P
