Relationship between uPA and NF-?B p65 expression and its clinical significance in breast cancer
- VernacularTitle:uPA与NF-?B p65在乳腺癌组织表达的相关性研究及临床病理意义
- Author:
Hong WANG
;
Jinmin WU
;
Houjun CAO
;
Wenpeng ZHOU
;
Yong FANG
;
Xing ZHANG
;
Shu ZHENG
- Publication Type:Journal Article
- Keywords:
Breast neoplasms;
Neoplasm invasiveness;
Neoplasm metastasis;
Urinary plasminogen activator
- From:
Chinese Journal of Pathophysiology
1989;0(06):-
- CountryChina
- Language:Chinese
-
Abstract:
AIM: To evaluate the relationship between uPA and NF-?B p65 expression and its clinical significance in breast cancer. METHODS: The uPA mRNA was measured by real-time fluorescent quantitative PCR in 46 cases of breast cancer tissues and their adjacent counterparts. NF-?B p65 were measured using immunohistochemistry. RESULTS: The expression of uPA gene was elevated in 63% of cases, and there was a strong correlation between NF-?B p65 and uPA expression (r=0.451,P
